Soilborne pathogens such as Phytophthora sojae and Phytophthora sansomeana cause substantial soybean yield losses. Integrating newly identified resistance genes, like Rps11, Rps14, and Rpsan1, into high-yielding varieties through precise marker-assisted selection enables development of cultivars with durable, multi-pathogen resistance. This genetic approach minimizes crop damage, stabilizes production, and lowers input costs.
In this Phase II project, we will further identify, characterize, and validate candidate genes underlying resistance to specific pathogens, and focus primarily on incorporating Rps11, Rps14, and Rpsan1 into public soybean breeding programs. Objectives include creating broad spectrum resistance to various pathogens by editing an atypical gene, which represses the expression of dozens to hundreds of disease resistant genes, development of DNA markers for precise selection of Rps11, Rps14 and Rpsan1; and introgression of these genes into soybean varieties of different maturity groups.
By improving host-plant resistance, soybean producers can achieve higher profitability through consistent yields, while the industry benefits from fewer disease-related supply chain disruptions and enhanced global competitiveness. Integrating diverse sources of resistance slows pathogen evolution and extends gene effectiveness. Ultimately, adopting disease-resistant cultivars promotes more sustainable and economical soybean production, benefiting both growers and the industry.